The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2012

Filed:

Dec. 14, 2009
Applicants:

Kieran Durkin, Folsom, CA (US);

Lawrence Emerson Fisher, Mountain View, CA (US);

Arthur Meili, Riehen, CH;

Michaelangelo Scalone, Fideris GR, CH;

Xianqing Shi, Clifton, NJ (US);

Justin Vitale, San Mateo, CA (US);

Inventors:

Kieran Durkin, Folsom, CA (US);

Lawrence Emerson Fisher, Mountain View, CA (US);

Arthur Meili, Riehen, CH;

Michaelangelo Scalone, Fideris GR, CH;

Xianqing Shi, Clifton, NJ (US);

Justin Vitale, San Mateo, CA (US);

Assignee:

Roche Palo Alto LLP, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/18 (2006.01); C07C 231/12 (2006.01); C07C 209/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2Ru(Z)(L)  j1;Ru(E)(E')(L)(D)  j2;wherein m, n, Ar, Y, RE, E′, D, Z and L are as defined herein.


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