The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 21, 2012

Filed:

Apr. 30, 2010
Applicants:

Gino Van Heeke, Horsham, GB;

Emma Hickman, Horsham, GB;

Henry Luke Danahay, Horsham, GB;

Pamela Tan, Basel, CH;

Anke Geick, Basel, CH;

Hans Peter Vornlocher, Basel, CH;

Inventors:

Gino Van Heeke, Horsham, GB;

Emma Hickman, Horsham, GB;

Henry Luke Danahay, Horsham, GB;

Pamela Tan, Basel, CH;

Anke Geick, Basel, CH;

Hans Peter Vornlocher, Basel, CH;

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides.


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