The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2012
Filed:
May. 06, 2005
Hyo Jeong Hong, Daejeon, KR;
Sang Jick Kim, Daejeon, KR;
Sun OK Yoon, Daejeon, KR;
Myeong Hee Jang, Daejeon, KR;
Keun Soo Kim, Daejeon, KR;
Tae Sup Lee, Seoul, KR;
Chang Woon Choi, Seoul, KR;
Hyo Jeong Hong, Daejeon, KR;
Sang Jick Kim, Daejeon, KR;
Sun Ok Yoon, Daejeon, KR;
Myeong Hee Jang, Daejeon, KR;
Keun Soo Kim, Daejeon, KR;
Tae Sup Lee, Seoul, KR;
Chang Woon Choi, Seoul, KR;
Korea Research Institute of Bioscience and Biotech, Daejeon, KR;
Abstract
The present invention relates to humanized antibodies specific to a tumor-associated glycoprotein, TAG-72, and anticancer compositions comprising the humanized antibodies. In detail, the present invention relates to a humanized antibody which has enhanced antigen binding affinity by mutating a heavy chain of a humanized antibody PXA/HzK specific for TAG-72, an antibody which is prepared by replacing a light chain of the humanized antibody with a human light chain, and anticancer compositions including the antibodies.