The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 21, 2012
Filed:
Jun. 27, 2008
Applicants:
Dinah Wen-yee Sah, Boston, MA (US);
R. Blake Pepinsky, Arlington, MA (US);
Paula Ann Boriack-sjodin, Waltham, MA (US);
Stephan S. Miller, Arlington, MA (US);
Anthony Rossomando, South Grafton, MA (US);
Laura Silvian, Waban, MA (US);
Inventors:
Dinah Wen-Yee Sah, Boston, MA (US);
R. Blake Pepinsky, Arlington, MA (US);
Paula Ann Boriack-Sjodin, Waltham, MA (US);
Stephan S. Miller, Arlington, MA (US);
Anthony Rossomando, South Grafton, MA (US);
Laura Silvian, Waban, MA (US);
Assignee:
Biogen Idec MA Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
Abstract
A dimer comprising a mutated neublastin polypeptide coupled to a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity relative to wild-type forms of neublastin.