The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2012

Filed:

Dec. 22, 2009
Applicants:

Kazuyuki Ohmoto, Osaka, JP;

Satoshi Itadani, Osaka, JP;

Yoshisuke Nakayama, Osaka, JP;

Jun Takeuchi, Osaka, JP;

Manabu Fujita, Osaka, JP;

Inventors:

Kazuyuki Ohmoto, Osaka, JP;

Satoshi Itadani, Osaka, JP;

Yoshisuke Nakayama, Osaka, JP;

Jun Takeuchi, Osaka, JP;

Manabu Fujita, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/04 (2006.01); A61K 31/405 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

As a compound having a potent oral activity and a long-lasting cysLT/cysLTreceptor antagonistic activity, the compound of the formula (I): which exhibits potent antagonistic activity against the cysLT/cysLTreceptor, and have long-lasting effects even in case of oral administration, and therefore is useful as an oral agent for preventing and/or treating a variety of diseases, for example, respiratory disease (for example, asthma (bronchial asthma, etc.), chronic obstructive pulmonary disease (COPD), pulmonary emphysema, chronic bronchitis, pneumonia (interstitial pneumonia, etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), apnea syndrome, allergic rhinitis, sinusitis (acute sinusitis, chronic sinusitis, etc.), pulmonary fibrosis, coughing (chronic coughing, etc.), and the like) was developed.


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