The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Oct. 24, 2007
Kyung-il Kim, Gyeonggi-do, KR;
Seung-bum Ha, Seoul, KR;
Jae-hoon Jeon, Daejeon, KR;
Soon-jeong Kwon, Gyeonggi-do, KR;
Yong-tae Kim, Daejeon, KR;
Ji-suk Yun, Gyeongsangbuk-do, KR;
Kyung-Il Kim, Gyeonggi-do, KR;
Seung-Bum Ha, Seoul, KR;
Jae-Hoon Jeon, Daejeon, KR;
Soon-Jeong Kwon, Gyeonggi-do, KR;
Yong-Tae Kim, Daejeon, KR;
Ji-Suk Yun, Gyeongsangbuk-do, KR;
Samchully Pharm. Co. Ltd., Seoul, KR;
Abstract
A method of preparing 2-deoxy-L-ribose represented by the following formula I is disclosed. The preparation method includes the steps of: treating L-arabinose with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-L-arabinopyranose; allowing the prepared 1-alkoxy-L-arabinopyranose to react with acyl chloride so as to prepare 1-alkoxy-2,3,4-triacyl-L-arabinopyranose; brominating the alkoxy group of the prepared 1-alkoxy-2,3,4-triacyl-L-arabinopyranose to prepare a 1-bromo-2,3,4-triacyl compound; allowing the prepared compound to react with zinc in the presence of ethyl acetate and an organic base so as to prepare glycal; treating the glycal with an alcohol solvent in the presence of an acid to prepare 1-alkoxy-2-deoxy-3,4-diacyl-L-ribopyranose; treating the prepared 1-alkoxy-2-deoxy-3,4-diacyl-L-ribopyranose with a base to prepare 1-alkoxy-2-deoxy-L-ribopyranose; and hydrolyzing the prepared 1-alkoxy-2-deoxy-L-ribopyranose in the presence of an acid catalyst.