The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Nov. 07, 2007
Paul J. Maddon, Scarsdale, NY (US);
Gerald P. Donovan, New York, NY (US);
William C. Olson, Ossining, NY (US);
Norbert Schuelke, Dedham, MA (US);
Jason Gardner, Merseyside, GB;
Dangshe MA, Milwood, NY (US);
Jaspal S. Kang, Surrey, CA;
Larry Green, San Francisco, CA (US);
Paul J. Maddon, Scarsdale, NY (US);
Gerald P. Donovan, New York, NY (US);
William C. Olson, Ossining, NY (US);
Norbert Schuelke, Dedham, MA (US);
Jason Gardner, Merseyside, GB;
Dangshe Ma, Milwood, NY (US);
Jaspal S. Kang, Surrey, CA;
Larry Green, San Francisco, CA (US);
PSMA Development Company, LLC, Tarrytown, NY (US);
Amgen Fremont Inc., Fremont, CA (US);
Abstract
The invention includes antibodies or antigen-binding fragments thereof which bind specifically to conformational epitopes on the extracellular domain of PSMA, compositions containing one or a combination of such antibodies or antigen-binding fragments thereof, hybridoma cell lines that produce the antibodies, and methods of using the antibodies or antigen-binding fragments thereof for cancer diagnosis and treatment. The invention also includes oligomeric forms of PSMA proteins, compositions comprising the multimers, and antibodies that selectively bind to the multimers.