The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Oct. 12, 2005
James C. Barrow, Harleysville, PA (US);
Craig A. Coburn, Royersford, PA (US);
Melissa S. Egbertson, Ambler, PA (US);
Georgia B. Mcgaughey, Harleysville, PA (US);
Melody A. Mcwherter, Boyertown, PA (US);
Lou Anne Neilson, Sellersville, PA (US);
Kenneth E. Rittle, Green Lane, PA (US);
Harold G. Selnick, Ambler, PA (US);
Shaun R. Stauffer, Schwenksville, PA (US);
Zhi-qiang Yang, Schwenksville, PA (US);
Wenjin Yang, Foster City, CA (US);
Wanli LU, Burlingame, CA (US);
Bruce Fahr, Foster City, CA (US);
James C. Barrow, Harleysville, PA (US);
Craig A. Coburn, Royersford, PA (US);
Melissa S. Egbertson, Ambler, PA (US);
Georgia B. McGaughey, Harleysville, PA (US);
Melody A. McWherter, Boyertown, PA (US);
Lou Anne Neilson, Sellersville, PA (US);
Kenneth E. Rittle, Green Lane, PA (US);
Harold G. Selnick, Ambler, PA (US);
Shaun R. Stauffer, Schwenksville, PA (US);
Zhi-Qiang Yang, Schwenksville, PA (US);
Wenjin Yang, Foster City, CA (US);
Wanli Lu, Burlingame, CA (US);
Bruce Fahr, Foster City, CA (US);
Merck, Sharp & Dohme Corp., Rahway, NJ (US);
Sunesis Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present invention is directed to spiropiperidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.