The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2012

Filed:

Jan. 09, 2006
Applicants:

Hyunsuk Shim, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

James P. Snyder, Atlanta, GA (US);

Weiqiang Zhan, Decatur, GA (US);

Zhongxing Liang, Tucker, GA (US);

Inventors:

Hyunsuk Shim, Atlanta, GA (US);

Dennis C. Liotta, Atlanta, GA (US);

James P. Snyder, Atlanta, GA (US);

Weiqiang Zhan, Decatur, GA (US);

Zhongxing Liang, Tucker, GA (US);

Assignee:

Emory University, Atlanta, GA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A01N 43/40 (2006.01); A61K 31/505 (2006.01); A61K 31/44 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds, pharmaceutical compositions and methods of use of certain compounds that are antagonists of the chemokine CXCR4 receptor for the treatment of proliferative conditions mediated by CXCR4 receptors. The compounds provided interfere with the binding of SDF1 to the receptor. These compounds are particularly useful for treating or reducing the severity of hyperproliferative diseases by inhibiting metastasis.


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