The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Mar. 17, 2006
Timo Heinrich, Gross-Umstadt, DE;
Andree Blaukat, Muehltal, DE;
Maria Kordowicz, Griesheim, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The invention relates to compounds of the formula (I), in which Ar denotes a mono- or bicyclic aromatic homo- or heterocycle having 1 to 4 N, O and/or S atoms and 5 to 10 skeleton atoms, which may be unsubstituted or mono-, di- or trisubstituted by carbonyl oxygen, Hal, A, OH, OA, NH, NHA, NA, NO, CN, OCN, SCN, COOH, COOA, CONH, CONHA, CONA, NHCOA, NHCONH, NHSOA, CHO, COA, SONHand/or S(O)A, A denotes unbranched, branched or cyclic alkyl having 1-14 C atoms, in which one or two CHgroups may be replaced by O or S atoms and/or by —CH═CH— groups and/or in addition 1-7 H atoms may be replaced by F and/or Cl, Hal: F, Cl, Br or I, D: NH, NH, NA, NHA, CH, CH, OH, OA, O or S, E: CH, CH, NH or N, Y: E or a saturated or unsaturated bond, X: CH, O or NH, Q: Hal, A, OH, OA, NH, NHA, NA, NO, CN, OCN, SCN, COOH, COOA, CONH, CONHA, CONA, NHCOA, NHCONH, NHSOA, CHO, COA, SONHor X-M, to the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumors and/or diseases in the development or course of which kinases are involved.