The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Oct. 31, 2007
Applicants:
John O. Trent, Louisville, KY (US);
Paula J. Bates, Louisville, KY (US);
Donald J. Miller, Louisville, KY (US);
Inventors:
John O. Trent, Louisville, KY (US);
Paula J. Bates, Louisville, KY (US);
Donald J. Miller, Louisville, KY (US);
Assignee:
Advanced Cancer Therapeutics, LLC, Louisville, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions and methods for modulating tumor proliferation in an individual are provided. The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the present invention can be used to modulate the proliferation of malignant, dysplastic, hyperproliferative, and/or metastatic cells through interference with molecular interactions and functions of nucleolin in the tumor cell.