The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 2012

Filed:

Nov. 17, 2006
Applicants:

Samuel E. Lynch, Franklin, TN (US);

Myron Nevins, Swampscott, MA (US);

Massimo Simion, Milan, IT;

Inventors:

Samuel E. Lynch, Franklin, TN (US);

Myron Nevins, Swampscott, MA (US);

Massimo Simion, Milan, IT;

Assignee:

BioMimetic Therapeutics, Inc., Franklin, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides effective new methods and materials for maxillofacial bone augmentation, particularly alveolar ridge augmentation, that are free of problems associated with prior art methods. In one embodiment, these materials include human recombinant platelet derived growth factor (rhPDGF-BB) and a biocompatible matrix. In another embodiment, these materials include rhPDGF-BB, a deproteinized bone block or calcium phosphate, and a bioresorbable membrane. The use of these materials in the present method is effective in regenerating maxillofacial bones and facilitating achievement of stable osseointegrated implants. The mandible and maxilla are preferred bones for augmentation, and enhancement of the alveolar ridge is a preferred embodiment of the present invention.


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