The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Sep. 19, 2007
Avindra Nath, Baltimore, MD (US);
Caroline F Anderson, Columbia, MD (US);
David Irani, Baltimore, MD (US);
Robert J Cotter, Baltimore, MD (US);
Joseph P Steiner, Mount Airy, MD (US);
Norman Haughey, Baltimore, MD (US);
Avindra Nath, Baltimore, MD (US);
Caroline F Anderson, Columbia, MD (US);
David Irani, Baltimore, MD (US);
Robert J Cotter, Baltimore, MD (US);
Joseph P Steiner, Mount Airy, MD (US);
Norman Haughey, Baltimore, MD (US);
The Johns Hopkins University, Baltimore, MD (US);
Abstract
Biological markers for multiple sclerosis, and their use in the diagnosis and prognosis of the disease, are described. Also described are methods for treating multiple sclerosis by administering an inhibitor of cathepsin B activity or a neuroprotective composition comprising a modified terpenoid compound. Also described are isolated polypeptide biomarkers, polynucleotides encoding the polypeptide biomarkers, and antibodies that bind specifically to the polypeptide biomarkers. Further described are kits that include the above-mentioned isolated polypeptide biomarkers, the polynucleotides encoding them, or specific antibodies against the polypeptide biomarkers.