The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Feb. 03, 2006
Catherine M. Rohloff, Los Altos, CA (US);
Guohua Chen, Sunnyvale, CA (US);
Andrew S. Luk, Castro Valley, CA (US);
Rupal A. Ayer, Cupertino, CA (US);
Paul R. Houston, Hayward, CA (US);
Michael A. Desjardin, Sunnyvale, CA (US);
Pauline Zamora, Sausalito, CA (US);
Stan Lam, Dublin, CA (US);
Catherine M. Rohloff, Los Altos, CA (US);
Guohua Chen, Sunnyvale, CA (US);
Andrew S. Luk, Castro Valley, CA (US);
Rupal A. Ayer, Cupertino, CA (US);
Paul R. Houston, Hayward, CA (US);
Michael A. Desjardin, Sunnyvale, CA (US);
Pauline Zamora, Sausalito, CA (US);
Stan Lam, Dublin, CA (US);
Intarcia Therapeutics, Inc., Hayward, CA (US);
Abstract
A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group consisting of benzyl benzoate, decanol, ethyl hexyl lactate, and mixtures thereof and the at least one polymer may be selected from the group consisting of a polyester, pyrrolidone, ester of an unsaturated alcohol, ether of an unsaturated alcohol, polyoxyethylenepolyoxypropylene block copolymer, and mixtures thereof. In one embodiment, the at least one solvent is benzyl benzoate and the at least one polymer is polyvinylpyrrolidone. A stable, nonaqueous suspension formulation that includes the nonaqueous, single-phase vehicle and an active agent, and a method of forming the same, are also disclosed.