The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 14, 2012
Filed:
Jun. 09, 2009
Stephen J. Caracci, Elmira, NY (US);
Volker H. O. Eckelt, Jena, DE;
Anthony G. Frutos, Painted Post, NY (US);
Mark F. Krol, Painted Post, NY (US);
Thomas C. Moore, Jena, DE;
David A. Pastel, Horseheads, NY (US);
Gordon M. Shedd, Lawrenceville, PA (US);
Stephen J. Caracci, Elmira, NY (US);
Volker H. O. Eckelt, Jena, DE;
Anthony G. Frutos, Painted Post, NY (US);
Mark F. Krol, Painted Post, NY (US);
Thomas C. Moore, Jena, DE;
David A. Pastel, Horseheads, NY (US);
Gordon M. Shedd, Lawrenceville, PA (US);
Corning Incorporated, Corning, NY (US);
Abstract
A screening system and method are described herein which provide a unique and practical solution for enabling label-free high throughput screening (HTS) to aid in the discovery of new drugs. In one embodiment, the screening system enables direct binding assays to be performed in which a biomolecular interaction of a chemical compound (drug candidate) with a biomolecule (therapeutic target) can be detected using assay volumes and concentrations that are compatible with the current practices of HTS in the pharmaceutical industry. The screening system also enables the detection of bio-chemical interactions that occur in the wells of a microplate which incorporates biosensors and surface chemistry to immobilize the therapeutic target at the surface of the biosensors. The screening system also includes fluid handling and plate handling devices to help perform automated HTS assays.