The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2012
Filed:
Apr. 14, 2010
Young Min Kim, Yongin-si, KR;
Dae Hae Song, Seoul, KR;
Sung Youb Jung, Suwon-si, KR;
Chang Hwan Kim, Suwon-si, KR;
IN Young Choi, Seongnam-si, KR;
SE Chang Kwon, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Young Min Kim, Yongin-si, KR;
Dae Hae Song, Seoul, KR;
Sung Youb Jung, Suwon-si, KR;
Chang Hwan Kim, Suwon-si, KR;
In Young Choi, Seongnam-si, KR;
Se Chang Kwon, Seoul, KR;
Gwan Sun Lee, Seoul, KR;
Hanmi Holdings Co., Ltd., Seoul, KR;
Abstract
Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs.