The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2012
Filed:
Jun. 06, 2008
Angela Brodie, Fulton, MD (US);
Vincent Njar, Glen Burnie, MD (US);
Gauri Sabnis, Catonsville, MD (US);
Lalji Gediya, Baltimore, MD (US);
Angela Brodie, Fulton, MD (US);
Vincent Njar, Glen Burnie, MD (US);
Gauri Sabnis, Catonsville, MD (US);
Lalji Gediya, Baltimore, MD (US);
University of Maryland, Baltimore, Baltimore, MD (US);
Abstract
The present invention relates to the methods of treating endocrine-regulated cancers, including hormone resistant cancers, for example. More specifically, the present invention relates to a method of increasing the sensitivity of hormone resistant cancers to hormonal therapeutic agents. In particular embodiments, the present invention concerns delivery of a histone deacetylase inhibitor and a hormone targeted drug to an individual with cancer. In specific embodiments, the histone deacetylase inhibitor and the hormone targeted drug act synergistically to treat the cancer, including by overcoming resistance to a cancer therapy.