The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 07, 2012

Filed:

Mar. 03, 2011
Applicants:

Scott R. Presnell, Tacoma, WA (US);

Darrell C. Conklin, Seattle, WA (US);

Julia E. Novak, Bainbridge Island, WA (US);

Angela K. Hammond, Issaquah, WA (US);

Inventors:

Scott R. Presnell, Tacoma, WA (US);

Darrell C. Conklin, Seattle, WA (US);

Julia E. Novak, Bainbridge Island, WA (US);

Angela K. Hammond, Issaquah, WA (US);

Assignee:

ZymoGenetics, Inc., Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/531 (2006.01); G01N 33/532 (2006.01); C07K 14/00 (2006.01); C07K 14/52 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zalpha11, are located on chromosome 16, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.


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