The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2012
Filed:
Jul. 28, 2008
Sathy V. Balu-iyer, Amherst, NY (US);
Robert Straubinger, Amherst, NY (US);
Karthik Ramani, Thiruvamiyur Chennai, IN;
Razvan D. Miclea, Simi Valley, CA (US);
Sathy V. Balu-Iyer, Amherst, NY (US);
Robert Straubinger, Amherst, NY (US);
Karthik Ramani, Thiruvamiyur Chennai, IN;
Razvan D. Miclea, Simi Valley, CA (US);
The Research Foundation of State University of New York, Amherst, NY (US);
Abstract
The present invention provides compositions and methods for reducing the immunogenicity and increasing the circulating half-life of therapeutic proteins such as Factor VIII. The compositions comprise lipidic structures such as liposomes, micelles and cochleates comprising a negatively charged lipid and polyethylene glycol derivatized phosphatidyl ethanolamine.