The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2012
Filed:
Nov. 04, 2009
Carroll Edward Ball, Los Angeles, CA (US);
Arkadij M. Elizarov, Woodland Hills, CA (US);
Hartmuth C. Kolb, Playa Del Rey, CA (US);
Reza Miraghaie, Culver City, CA (US);
Jianzhong Zhang, Brea, CA (US);
Carroll Edward Ball, Los Angeles, CA (US);
Arkadij M. Elizarov, Woodland Hills, CA (US);
Hartmuth C. Kolb, Playa Del Rey, CA (US);
Reza Miraghaie, Culver City, CA (US);
Jianzhong Zhang, Brea, CA (US);
Siemens Medical Solutions USA, Inc., Malvern, PA (US);
Abstract
Methods and apparatus for facilitating the synthesis of compounds in a batch device are presented. Application of the batch type microfluidic devices to the synthesis of radiolabeled compounds is described. These methods and apparatus enable the selective introduction of multiple reagents via an enhanced rotary flow distribution valve through a single inlet port of the synthetic device. The sequential introduction of multiple reagents through a single inlet port allows an optimal delivery of highly concentrated reagents into the reactor and facilitates the synthesis of the desired products with a minimal loss of materials during transfers, which is critical to the synthesis of radiolabeled biomarkers.