The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2012
Filed:
Aug. 30, 2007
Takashi Inagaki, Hirakata, JP;
Yoshikazu Yamakawa, Hirakata, JP;
Takashi Inagaki, Hirakata, JP;
Yoshikazu Yamakawa, Hirakata, JP;
Dainippon Sumitomo Pharma Co., Ltd., Osaka, JP;
Katayama Seiyakusyo Co., Ltd., Osaka, JP;
Abstract
The present invention provides with a process of preparing an optically active succinimide derivative, which is a key intermediate for production of ranirestat. A compound (3) is easily prepared by treating the derivative of succinic acid diester of the formula (2): wherein Ris an amino group protected with a group removed by hydrogenolysis or a tert-butoxycarbonylamino group and Ris an ethyl group optionally substituted with one or two methyl group(s) at α-position, provided that Ris not a tert-butyl group when Ris a tert-butoxycarbonylamino group; with alkali metal alkoxide and the compound (3) can be an important intermediate for production of ranirestat.