The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2012
Filed:
Sep. 17, 2008
Applicants:
Hans-jochen Lang, Frankfurt am Main, DE;
John Weston, Frankfurt am Main, DE;
Uwe Heinelt, Frankfurt am Main, DE;
Inventors:
Hans-Jochen Lang, Frankfurt am Main, DE;
John Weston, Frankfurt am Main, DE;
Uwe Heinelt, Frankfurt am Main, DE;
Assignee:
Sanofi-Aventis, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to NHE-3 inhibitor compounds of formula I: In which R1-R11 are more specifically defined herein. These substituted 2-amino-4-phenyl-dihydroquinolines are useful the treatment of various renal and respiratory disorders such as acute or chronic renal failure, for impairments of biliary function and respiratory impairments such as snoring, sleep apneas or stroke. Formulations comprising them and methods for their use are also described herein.