The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2012
Filed:
Nov. 29, 2006
Takahiro Kuramochi, Tokyo, JP;
Ryoji Hirabayashi, Tokyo, JP;
Yohei Koganemaru, Tokyo, JP;
Ryosuke Munakata, Tokyo, JP;
Koichi Yonezawa, Tokyo, JP;
Tetsuo Kiso, Tokyo, JP;
Takahiro Kuramochi, Tokyo, JP;
Ryoji Hirabayashi, Tokyo, JP;
Yohei Koganemaru, Tokyo, JP;
Ryosuke Munakata, Tokyo, JP;
Koichi Yonezawa, Tokyo, JP;
Tetsuo Kiso, Tokyo, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
To provide a novel and excellent agent for treating or preventing nociceptive pain, neuropathic pain, cancer pain, headache, bladder function disorder and the like, based on the inhibitory action on the capsaicin receptor VR1 activation. The present invention was accomplished by confirming that a benzamide derivative characterized by the possession of a benzene ring in which a single ring is condensed on the nitrogen atom of amido group and possession of a lower alkylamino or an amino group substituted with a ring group at the neighboring position of said amido group has a strong inhibitory action on VR1 activation and excellent pharmacological actions based on this and by finding that it can become an excellent agent for treating or preventing VR1-involved diseases such as nociceptive pain, neuropathic pain, cancer pain, headache, bladder function disorder and the like.