The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2012
Filed:
Dec. 02, 2009
Zuosheng Liu, San Diego, CA (US);
Jon Loren, San Diego, CA (US);
Valentina Molteni, San Diego, CA (US);
Juliet Nabakka, San Diego, CA (US);
Zuosheng Liu, San Diego, CA (US);
Jon Loren, San Diego, CA (US);
Valentina Molteni, San Diego, CA (US);
Juliet Nabakka, San Diego, CA (US);
IRM LLC, Hamilton, BM;
Abstract
The invention provides compounds of Formula (2), and pharmaceutical compositions thereof, wherein R, R, R, Rand L are as described herein; as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit, PDGFRα, PDGFRβ, CSF1R, Abl, BCR-Abl, CSK, JNK1, JNK2, p38, p70S6K, TGFβ, SRC, EGFR, trkB, FGFR3, FLT3, Fes, Lck, Syk, RAF, MKK4, MKK6, SAPK2β, BRK, KDR, c-raf or b-raf kinase, or mutant forms thereof.