The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2012

Filed:

Oct. 22, 2008
Applicants:

Leslie Jean Holsinger, Los Altos, CA (US);

Kyle Elrod, Belmont, CA (US);

John O. Link, San Francisco, CA (US);

Michael Graupe, Pacifica, CA (US);

IN Jong Kim, Lexington, MA (US);

Inventors:

Leslie Jean Holsinger, Los Altos, CA (US);

Kyle Elrod, Belmont, CA (US);

John O. Link, San Francisco, CA (US);

Michael Graupe, Pacifica, CA (US);

In Jong Kim, Lexington, MA (US);

Assignee:

ViroBay, Inc., Menlo Park, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds of formula I, below, that have the dual property of acting as cathepsin S inhibitors and of inhibiting HCV replication. Such compounds are therefore useful in treating disease states that include hepatitis C, Alzheimer's disease, and autoimmune disorders. The present invention is also directed to pharmaceutical compositions containing these compounds, and processes for preparing the compounds.


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