The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2012

Filed:

May. 19, 2010
Applicants:

Gianni Chessari, Cambridge, GB;

Maria Grazia Carr, Luton, GB;

Miles Stuart Congreve, Cambridge, GB;

Robert Downham, Newmarket, GB;

Martyn Frederickson, Cambridge, GB;

Christopher William Murray, Cambridge, GB;

Eva Figueroa Navarro, Cambridge, GB;

Michael Alistair O'brien, Hertz, GB;

Theresa Rachel Phillips, Macclesfield, GB;

Andrew James Woodhead, Cambridge, GB;

Inventors:

Gianni Chessari, Cambridge, GB;

Maria Grazia Carr, Luton, GB;

Miles Stuart Congreve, Cambridge, GB;

Robert Downham, Newmarket, GB;

Martyn Frederickson, Cambridge, GB;

Christopher William Murray, Cambridge, GB;

Eva Figueroa Navarro, Cambridge, GB;

Michael Alistair O'Brien, Hertz, GB;

Theresa Rachel Phillips, Macclesfield, GB;

Andrew James Woodhead, Cambridge, GB;

Assignee:

Astex Therapeutics, Ltd., Cambridge, GB;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/445 (2006.01); A61K 31/405 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides methods for treating cancer, particularly hematopoietic tumors of lymphoid or myeloid lineage, prostate cancer, lung cancer, gastrointestinal stromal tumor, breast cancer and melanoma, which comprise administering to the mammal a compound, salt, hydrate, tautomer or N-oxide according to formula (I): and in particular, those of subgenus VIIa These compounds inhibit or modulate the activity of the heat shock protein Hsp90.


Find Patent Forward Citations

Loading…