The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 31, 2012
Filed:
Nov. 14, 2004
Ariel Notcovich, Haifa, IL;
Alon Herschhorn, Nesher, IL;
Shai Nimri, Kibbutz Sarid, IL;
John Barich, Pleasant Hill, CA (US);
Ariel Lipson, Haifa, IL;
Ran Boaz, Haifa, IL;
Doron Lipson, Tel Aviv, IL;
Yaakov Levie, Misgav, IL;
Ariel Notcovich, Haifa, IL;
Alon Herschhorn, Nesher, IL;
Shai Nimri, Kibbutz Sarid, IL;
John Barich, Pleasant Hill, CA (US);
Ariel Lipson, Haifa, IL;
Ran Boaz, Haifa, IL;
Doron Lipson, Tel Aviv, IL;
Yaakov Levie, Misgav, IL;
Bio-Rad Haifa Ltd., Technion, Haifa, IL;
Abstract
A method for determining one or more kinetic parameters of binding between a first binding member and a second binding member. The method comprises adsorbing the first binding member to a surface at a plurality of microspots. The second binding member is then presented to the first binding member at each of the microspots, there being a plurality of combinations of first binding member surface density and second binding member concentration among the plurality of microspots. Data indicative of a binding reaction between the first of microspots are then obtained and analyzed so as to obtain one or more kinetic parameters of the binding between the first and second binding members. The invention also provides a system for carrying out the method. A method for localizing a molecular species at microspots on a surface, and a probe array produced by the method are also provided.