The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2012

Filed:

Jul. 18, 2011
Applicants:

Tammy H. Huang, Golden Bridge, NY (US);

Sean Stevens, San Francisco, CA (US);

Joel H. Martin, Putnam Valley, NY (US);

Jeanette L. Fairhurst, White Plains, NY (US);

Kevin J. Pobursky, Beacon, NY (US);

Margaret Karow, Camarillo, CA (US);

Joan A. Windsor, Brooklyn, NY (US);

Warren R. Mikluka, Brewster, NY (US);

Inventors:

Tammy H. Huang, Golden Bridge, NY (US);

Sean Stevens, San Francisco, CA (US);

Joel H. Martin, Putnam Valley, NY (US);

Jeanette L. Fairhurst, White Plains, NY (US);

Kevin J. Pobursky, Beacon, NY (US);

Margaret Karow, Camarillo, CA (US);

Joan A. Windsor, Brooklyn, NY (US);

Warren R. Mikluka, Brewster, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 15/12 (2006.01); C12N 15/64 (2006.01);
U.S. Cl.
CPC ...
Abstract

An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18Rα), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.


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