The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 2012

Filed:

Jun. 18, 2004
Applicants:

Gregory D. Plowman, San Carlos, CA (US);

Felix D. Karim, Walnut Creek, CA (US);

Candace Swimmer, San Francisco, CA (US);

Hinrich Alexander Habeck, Tuebingen, DE;

Thomas I. Koblizek, Tuebingen, DE;

Stefan Schulte-merker, Utrecht, DE;

Ulrike Eisenmann, Tutzig, DE;

Gordon Mark Stott, San Francisco, CA (US);

Torsten Trowe, San Francisco, CA (US);

Andreas Michael Vogel, Basel, CH;

Joerg Heinrich Odenthal, Tuebingen, DE;

Jochen Konrad Scheel, San Carlos, CA (US);

Torsten Tilmann Will, Bielefeld, DE;

Yinsheng Jin, Pinceton, NJ (US);

Lynn Margaret Bjerke, Sutton, GB;

Timothy S. Heuer, El Granada, CA (US);

Inventors:

Gregory D. Plowman, San Carlos, CA (US);

Felix D. Karim, Walnut Creek, CA (US);

Candace Swimmer, San Francisco, CA (US);

Hinrich Alexander Habeck, Tuebingen, DE;

Thomas I. Koblizek, Tuebingen, DE;

Stefan Schulte-Merker, Utrecht, DE;

Ulrike Eisenmann, Tutzig, DE;

Gordon Mark Stott, San Francisco, CA (US);

Torsten Trowe, San Francisco, CA (US);

Andreas Michael Vogel, Basel, CH;

Joerg Heinrich Odenthal, Tuebingen, DE;

Jochen Konrad Scheel, San Carlos, CA (US);

Torsten Tilmann Will, Bielefeld, DE;

Yinsheng Jin, Pinceton, NJ (US);

Lynn Margaret Bjerke, Sutton, GB;

Timothy S. Heuer, El Granada, CA (US);

Assignee:

Exelixis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Human MYLK genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MYLK are provided.


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