The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2012

Filed:

Feb. 04, 2008
Applicants:

Nadia M. J. Rupniak, Cary, NC (US);

James F. White, Carlisle, MA (US);

Kazumi Shiosaki, Wellesley, MA (US);

J. David Leander, Indianapolis, IN (US);

Shoucheng Du, Pittsburgh, PA (US);

Daniel J. Coughlin, Hackettstown, NJ (US);

Inventors:

Nadia M. J. Rupniak, Cary, NC (US);

James F. White, Carlisle, MA (US);

Kazumi Shiosaki, Wellesley, MA (US);

J. David Leander, Indianapolis, IN (US);

Shoucheng Du, Pittsburgh, PA (US);

Daniel J. Coughlin, Hackettstown, NJ (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/22 (2006.01); C07D 267/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds that inhibit cholinesterase activity and, upon hydrolysis release a pharmacologically active agent. The compounds of the invention are employed in methods to treat an individual. The pharmacologically active agent obtained by hydrolysis of the compound can treat, for example, a nervous system condition, a cholinergic deficiency and conditions or diseases associated with a deficiency in a pharmacologically active agent, such as acetylcholine.


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