The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2012
Filed:
Aug. 17, 2010
Paolo Carminati, Rome, IT;
Maria Ornella Tinti, Rome, IT;
Mauro Marzi, Rome, IT;
Fabrizio Giorgi, Rome, IT;
Walter Cabri, Rodano, IT;
Marco Alpegiani, Rodano, IT;
Domenico Vergani, Rodano, IT;
Paolo Ghetti, Rodano, IT;
Paolo Carminati, Rome, IT;
Maria Ornella Tinti, Rome, IT;
Mauro Marzi, Rome, IT;
Fabrizio Giorgi, Rome, IT;
Walter Cabri, Rodano, IT;
Marco Alpegiani, Rodano, IT;
Domenico Vergani, Rodano, IT;
Paolo Ghetti, Rodano, IT;
Abstract
A stereoselective process for preparing 7-[(E)-t-butyloxyiminomethyl]-camptothecin (also known as gimatecan) is herein disclosed. With the addition of further dissolution and precipitation steps carried out in appropriate different solvent mixtures, four new crystalline forms of gimatecan are also obtainable by using the same stereoselective process.