The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2012
Filed:
Nov. 19, 2008
Applicants:
Vickie L. Brown-driver, Solana Beach, CA (US);
Ravi Jain, Fremont, CA (US);
Inventors:
Vickie L. Brown-Driver, Solana Beach, CA (US);
Ravi Jain, Fremont, CA (US);
Assignee:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12N 5/00 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided.