The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2012

Filed:

Aug. 23, 2010
Applicants:

Dan Peters, Malmö, SE;

Gunnar M. Olsen, Smørum, DK;

Elsebet Østergaard Nielsen, København K, DK;

Daniel B. Timmermann, Herlev, DK;

Steven Charles Loechel, Frederiksberg, DK;

Inventors:

Dan Peters, Malmö, SE;

Gunnar M. Olsen, Smørum, DK;

Elsebet Østergaard Nielsen, København K, DK;

Daniel B. Timmermann, Herlev, DK;

Steven Charles Loechel, Frederiksberg, DK;

Assignee:

Neurosearch A/S, Ballerup, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/00 (2006.01); A61K 31/551 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.


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