The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2012
Filed:
Apr. 28, 2004
Hiroshi Miura, Fuji, JP;
Makoto Kanebako, Shizuoka, JP;
Masayuki Kanishi, Numadu, JP;
Yasuo Shinoda, Shizuoka, JP;
Toshio Inagi, Mishima, JP;
Hirofumi Takeuchi, Gifu, JP;
Hiroshi Miura, Fuji, JP;
Makoto Kanebako, Shizuoka, JP;
Masayuki Kanishi, Numadu, JP;
Yasuo Shinoda, Shizuoka, JP;
Toshio Inagi, Mishima, JP;
Hirofumi Takeuchi, Gifu, JP;
Kowa Co., Ltd., Nagoya-shi, JP;
Abstract
A composition containing a very low water-soluble drug, which composition is produced by treating, with a supercritical or subcritical carbon dioxide fluid, a mixture containing a very low water-soluble drug and a porous material (exclusive of a porous silica material characterized in that the material has an average pore diameter of 1 to 20 nm, the total pore volume of the material that have a diameter falling within a range of ±40% of the average pore diameter account for 60% or more the volume of all the pores of the material, and, when subjected to X-ray diffractometry, the material exhibits one or more peaks at a diffraction angle (2θ) corresponding to d of 1 nm or more); and a method for producing the composition. The very-low-water-soluble-drug-containing composition of the present invention ensures improved dissolution of the very low water-soluble drug.