The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 24, 2012
Filed:
Feb. 16, 2007
Applicants:
Adam R. Mezo, Waltham, MA (US);
Kevin A. Mcdonnell, Waltham, MA (US);
Cristina A. Tan Hehir, Niskayuna, NY (US);
Alfredo Castro, Winchester, MA (US);
Inventors:
Adam R. Mezo, Waltham, MA (US);
Kevin A. McDonnell, Waltham, MA (US);
Cristina A. Tan Hehir, Niskayuna, NY (US);
Alfredo Castro, Winchester, MA (US);
Assignee:
Syntonix Pharmaceuticals, Inc., Waltham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.