The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 24, 2012

Filed:

Aug. 13, 2009
Applicants:

Robert E. Hurst, Oklahoma City, OK (US);

Michael A. Ihnat, Tuttle, OK (US);

Inventors:

Robert E. Hurst, Oklahoma City, OK (US);

Michael A. Ihnat, Tuttle, OK (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 49/14 (2006.01); A61K 31/33 (2006.01); A61K 31/215 (2006.01); A61K 31/165 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
Abstract

In vitro and in vivo methods for identifying compounds capable of targeting suppressed cancer cells such as micrometastatic cells. The in vitro method includes the steps of comparing the response to a test compound of cancer cells grown on a suppressing cell support matrix which causes suppression of a malignant phenotype in a growing cancer cell and on a non-suppressing cell support matrix. The in vivo method includes a step of co-injecting labeled cancer cells with a malignant-phenotype suppressing matrix into a test animal to produce suppressed micrometastatic cells therein.


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