The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2012

Filed:

Apr. 14, 2008
Applicants:

Jean-marie Parel, Miami Shores, FL (US);

Fabrice Manns, Coral Gables, FL (US);

David S. Robinson, Kansas City, MO (US);

Peter Milne, Miami, FL (US);

David B. Denham, Miami, FL (US);

Xochitl Gonzalez-cirre, Madrid, ES;

Inventors:

Jean-Marie Parel, Miami Shores, FL (US);

Fabrice Manns, Coral Gables, FL (US);

David S. Robinson, Kansas City, MO (US);

Peter Milne, Miami, FL (US);

David B. Denham, Miami, FL (US);

Xochitl Gonzalez-Cirre, Madrid, ES;

Assignee:

University of Miami, Miami, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of thermally inducing and monitoring changes to localized regions of tissue illuminating a volume of tissue with a first beam of X-rays, detecting the portions of the first beam of X-rays that passed through the volume of tissue, generating a first X-ray image signal from the portions of X10 rays of the first beam detected, applying heat to at least a localized region of tissue within the volume of tissue after the illuminating and after the detecting, illuminating the volume of tissue with a second beam of X-rays, detecting portions of the second beam of X-rays that passed through the volume of tissue during the illuminating with the second beam of X-rays, generating a second X-ray image signal from the portions of X-rays of the second beam detected, and generating a difference image signal based upon a comparison of the first and second X-ray image signals. The difference image signal provides information of changes in X-ray attenuation by localized regions of tissue within the volume of tissue due to the application of heat.


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