The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8097742 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 17, 2012

Filed:

Jan. 20, 2005
Applicants:

Jackie Y. Ying, Singapore, SG;

Nikhil R. Jana, Singapore, SG;

Yuangang Zheng, Singapore, SG;

Inventors:

Jackie Y. Ying, Singapore, SG;

Nikhil R. Jana, Singapore, SG;

Yuangang Zheng, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a process for the preparation of a surface-functionalized nanoparticle comprising: (a) reacting a nanoparticle with a functionalized silane and a base in a substantially non-aqueous solvent to obtain a partially conjugated silanated nanoparticle, wherein the functionalized silane and the base are present in relative amounts such that said functionalized silane undergoes substantially only a single hydrolysis reaction; (b) reacting the partially conjugated silanated nanoparticle formed in step (a) with a base in a solvent in which the partially conjugated silanated nanoparticle is substantially insoluble and in which the base is substantially soluble. The invention also provides a surface-functionalized nanoparticle prepared therefrom and a bioconjugate comprising said a surface-functionalized nanoparticle.


Find Patent Forward Citations

Ying, Jackie. (2012). Water-soluble, surface-functionalized nanoparticle for bioconjugation via universal silane coupling (U.S. Patent No. 8097742). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8097742

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…