The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 17, 2012
Filed:
Dec. 20, 2007
Applicants:
Jorge Medrano Rupérez, Barcelona, ES;
Julio Campon Pardo, Barcelona, ES;
Laia Elías Rius, Barcelona, ES;
Ramón Berenguer Maimó, Barcelona, ES;
Inventors:
Jorge Medrano Rupérez, Barcelona, ES;
Julio Campon Pardo, Barcelona, ES;
Laia Elías Rius, Barcelona, ES;
Ramón Berenguer Maimó, Barcelona, ES;
Assignee:
Esteve Quimica, S.A., Barcelona, ES;
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/16 (2006.01); C07D 473/40 (2006.01);
U.S. Cl.
CPC ...
Abstract
Process for the preparation of abacavir, or its salts or its solvates comprising the step of reacting a compound (IV) where Ris a (C-C)-alkyl radical with anhydrous hydrochloric acid/(C-C)-alcohol, and then with tri(C-C)-alkyl orthoformate, in the absence of water. The preparation process may include further steps of reacting the compound obtained with cyclopropylamine and subsequently hydrolysis to yield abacavir.