The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 2012

Filed:

Aug. 23, 2010
Applicants:

Fernando Pedro Cossio, Leioa, ES;

Eneko Aldaba Arevalo, Leioa, ES;

Yosu Ion Vara Salazar, Leioa, ES;

Aizpea Zubia Olascoaga, Leioa, ES;

Silvia Vivanco Amato, Leioa, ES;

Miren Lorea Mendoza Arteche, Derio, ES;

Clarisa Salado Pogonza, Derio, ES;

Natalia Gallot Escobal, Derio, ES;

Fernando Vidal Vanaclocha, Derio, ES;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); C07C 251/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is related to new nitrogenated trans-stilbene compounds, more specifically, imine, pyrrole and indole derivatives, with procedures for the preparation and use thereof as pharmaceutical compositions for the treatment and/or chemoprevention of those mammalian diseases such as cancer, fibrosclerosis and acute/chronic inflammation, graft-versus-host reaction, ischemic-reperfusion tissue injury in stroke and heart attack, neurodegeneration, and during organ transplantation, whose pathogenic and pathophysiological mechanisms depend on or are significantly contributed by undesirable oxidative stress, angiogenic and proliferative responses.


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