The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2012
Filed:
Dec. 06, 2006
Atsushi Ochiai, Kashiwa, JP;
Emi Hosaka, Stuttgart, DE;
Kazuyasu Nakamura, Machida, JP;
Akiko Furuya, Machida, JP;
Yuji Ohki, Machida, JP;
Atsushi Ochiai, Kashiwa, JP;
Emi Hosaka, Stuttgart, DE;
Kazuyasu Nakamura, Machida, JP;
Akiko Furuya, Machida, JP;
Yuji Ohki, Machida, JP;
Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;
Japan as Represented by President of National Cancer Center, Tokyo, JP;
Abstract
An antibody which binds to a polypeptide encoded by human PERP (p53 apoptosis effector related to PMP-22) gene which is considered to be related to incidence of cancer or the like is desired. The present invention provides a gene recombinant antibody which has no consensus sequence of an N-linked sugar chain in a variable region, specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by the PERP gene and binds to the extracellular region. The antibody is useful for treatment of various diseases expressing a polypeptide encoded by the PERP gene.