The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 10, 2012

Filed:

Dec. 12, 2007
Applicants:

David J. Augeri, Princeton, NJ (US);

Marianne Carlsen, Yardley, PA (US);

Kenneth G. Carson, Princeton, NJ (US);

Qinghong Fu, Plainsboro, NJ (US);

Alexander Heim-riether, Newtown, CT (US);

Theodore C. Jessop, Lawrenceville, NJ (US);

James E. Tarver, Morrisville, PA (US);

Jerry A. Taylor, Trenton, NJ (US);

Inventors:

David J. Augeri, Princeton, NJ (US);

Marianne Carlsen, Yardley, PA (US);

Kenneth G. Carson, Princeton, NJ (US);

Qinghong Fu, Plainsboro, NJ (US);

Alexander Heim-Riether, Newtown, CT (US);

Theodore C. Jessop, Lawrenceville, NJ (US);

James E. Tarver, Morrisville, PA (US);

Jerry A. Taylor, Trenton, NJ (US);

Assignee:

Lexicon Pharmaceuticals, Inc., The Woodlands, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/47 (2006.01); C07D 403/04 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
Abstract

4-Amino-1H-pyrimidin-2-one-based compounds, compositions comprising them, and methods of their use for the treatment, prevention and management of various diseases and disorders are disclosed. Particular compounds are of formula I:


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