The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 10, 2012
Filed:
Sep. 20, 2006
Nicola J. Nasser, Nazareth, IL;
Aaron Avivi, D.N. Misgav, IL;
Israel Vlodavsky, Mevasseret Zion, IL;
Eviatar Nevo, Haifa, IL;
Nicola J. Nasser, Nazareth, IL;
Aaron Avivi, D.N. Misgav, IL;
Israel Vlodavsky, Mevasseret Zion, IL;
Eviatar Nevo, Haifa, IL;
Carmel-Haifa University Economic Corp. Ltd., Mount Carmel, IL;
Abstract
The invention relates to novel heparanases, heparanase splice variants, and to polynucleotides encoding them. Particularly, the invention relates toheparanases, and toand human heparanase splice variants. Heparanase splice variants can be used, for example, to modulate the activity of heparanase in diseases disorders or conditions caused by or associated with the enzymatic activity of heparanase. For instance, a splice variant capable of down regulating the activity of heparanase can be used to treat primary tumors and/or to prevent or treat metastasis.