The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2012

Filed:

Jul. 09, 2007
Applicants:

Daniel Romo, College Station, TX (US);

Huda Henry-riyad, Toronto, CA;

Changsuk Lee, College Station, TX (US);

Henry Nguyen, College Station, TX (US);

Vikram C. Purohit, Bryan, TX (US);

Seongho OH, Singapore, SG;

Inventors:

Daniel Romo, College Station, TX (US);

Huda Henry-Riyad, Toronto, CA;

Changsuk Lee, College Station, TX (US);

Henry Nguyen, College Station, TX (US);

Vikram C. Purohit, Bryan, TX (US);

Seongho Oh, Singapore, SG;

Assignee:

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a concise synthetic method for generating lactam-fused beta-lactones that feature, in some embodiments, a tertiary fused carbinol, quaternary carbons, and a reactive beta-lactone moiety available for further reactions. The present invention further provides compounds synthesized by this method as well as methods of using these compounds as inhibitors of the proteasome and fatty acid synthase.


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