The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2012

Filed:

Aug. 25, 2009
Applicants:

Kenji Kawashima, Ikoma, JP;

Noriko Kawashima, Ikoma, JP;

Hiroshi Enomoto, Ikoma, JP;

Minoru Yamamoto, Ikoma, JP;

Masaaki Murai, Ikoma, JP;

Inventors:

Kenji Kawashima, Ikoma, JP;

Noriko Kawashima, Ikoma, JP;

Hiroshi Enomoto, Ikoma, JP;

Minoru Yamamoto, Ikoma, JP;

Masaaki Murai, Ikoma, JP;

Assignee:

Santen Pharmaceutical Co., Ltd., Osaka-Shi, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4025 (2006.01); A61K 31/401 (2006.01); C07D 207/34 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound represented by the following formula (1) or a salt thereof: The compound has an inhibitory activity on the production of interleukin-6, and is therefore useful as a therapeutic agent for a disease associated with interleukin-6, ocular inflammatory diseases and the like. In the formula, Rrepresents a halogen atom, a hydrogen atom, a lower alkyl group which may have a substituent, a formyl group, or a lower alkylcarbonyl group which may have a substituent, Rrepresents a bicyclic hydrocarbon group which may have a substituent or a bicyclic heterocyclic group which may have a substituent, Rrepresents a hydrogen atom, a lower alkyl group which may have a substituent, an aryl group which may have a substituent, or an acyl group.


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