The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2012

Filed:

Sep. 28, 2007
Applicants:

Adam Antoni Galan, Alameda, CA (US);

Jeff Chen, San Francisco, CA (US);

Hongwang Du, Millbrae, CA (US);

Timothy Forsyth, Hayward, CA (US);

Tai Phat Huynh, Oakland, CA (US);

Henry William Beecroft Johnson, San Bruno, CA (US);

Patrick Kearney, San Francisco, CA (US);

James W. Leahy, San Leandro, CA (US);

Matthew Sangyup Lee, San Francisco, CA (US);

Grace Mann, San Mateo, CA (US);

Brian Hugh Ridgway, Belmont, CA (US);

Craig Stacy Takeuchi, Burlingame, CA (US);

Peiwen Zhou, Palo Alto, CA (US);

Inventors:

Adam Antoni Galan, Alameda, CA (US);

Jeff Chen, San Francisco, CA (US);

Hongwang Du, Millbrae, CA (US);

Timothy Forsyth, Hayward, CA (US);

Tai Phat Huynh, Oakland, CA (US);

Henry William Beecroft Johnson, San Bruno, CA (US);

Patrick Kearney, San Francisco, CA (US);

James W. Leahy, San Leandro, CA (US);

Matthew Sangyup Lee, San Francisco, CA (US);

Grace Mann, San Mateo, CA (US);

Brian Hugh Ridgway, Belmont, CA (US);

Craig Stacy Takeuchi, Burlingame, CA (US);

Peiwen Zhou, Palo Alto, CA (US);

Assignee:

Exelixis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/4439 (2006.01); A61K 31/4184 (2006.01); C07D 413/14 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention.


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