The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2012
Filed:
Aug. 07, 2008
Youngro Byun, Seoul, KR;
E Sak Lee, Seoul, KR;
Ok-cheol Jeon, Seoul, KR;
Sang Yoon Kim, Seoul, KR;
Rang-woon Park, Dae gu, KR;
Youngro Byun, Seoul, KR;
E Sak Lee, Seoul, KR;
Ok-cheol Jeon, Seoul, KR;
Sang Yoon Kim, Seoul, KR;
Rang-Woon Park, Dae gu, KR;
Mediplex Corporation, Korea, Seoul, KR;
Abstract
Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed between the bile acid and the heparin. Another embodiment includes a targeting moiety bonded to the heparin-bile acid conjugate through a spacer. Another illustrative heparin conjugate includes heparin covalently bonded to a sulfonated moiety, such as a naphthalene trisulfonate residue. A method of treating cancer includes administering a heparin conjugate to an individual in need thereof.