The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 2012
Filed:
Oct. 22, 2007
Applicants:
Ruth Franks, Granta Park, GB;
Mark Terence Liddament, Granta Park, GB;
Lutz Ulrich Jochen Wilhelm Jermutus, Granta Park, GB;
Andrew Grier Buchanan, Granta Park, GB;
Inventors:
Ruth Franks, Granta Park, GB;
Mark Terence Liddament, Granta Park, GB;
Lutz Ulrich Jochen Wilhelm Jermutus, Granta Park, GB;
Andrew Grier Buchanan, Granta Park, GB;
Assignee:
MedImmune Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/47 (2006.01); C12P 21/04 (2006.01); C12P 21/06 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Protein variants of CTLA-4, which show increased activity compared to wild-type in a cell assay and which exhibit increased stability. Such variants are useful for treatment of disorders whereby attenuation of the T cell response would be beneficial.