The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2012

Filed:

Jul. 06, 2007
Applicants:

Graeme L. Fraser, Rixensart, BE;

Hamid R. Hoveyda, Québec, CA;

Mark L. Peterson, Sherbrooke, CA;

Inventors:

Graeme L. Fraser, Rixensart, BE;

Hamid R. Hoveyda, Québec, CA;

Mark L. Peterson, Sherbrooke, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C07K 5/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective agonists of the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and variants thereof). Such compounds are useful as medicaments for treatment and prevention of a range of medical conditions characterized by disturbed gastrointestinal motility including, but not limited to, post-surgical gastroparesis and post-operative ileus in combination with opioid-induced bowel dysfunction. These agents are effective for multiple disorders at dose levels equivalent to those required to treat a single disorder.


Find Patent Forward Citations

Fraser, Graeme. (2012). Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders (U.S. Patent No. 8088733). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8088733

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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