The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 2012

Filed:

Feb. 23, 2006
Applicants:

Andre Leonardus DE Roos, Delft, NL;

Pieter Marinus Van Den Broecke, Didam, NL;

Luppo Edens, Rotterdam, NL;

Inventors:

Andre Leonardus De Roos, Delft, NL;

Pieter Marinus Van Den Broecke, Didam, NL;

Luppo Edens, Rotterdam, NL;

Assignee:

DSM IP Assets B.V., Heerlen, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); A61K 38/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process to produce IPP from a protein source whereby the protein source comprises a protein having the -I-P-P- sequence and having in the protein amino acid sequence at least 6 times more -I-P-P- present than -V-P-P- (molar basis) which comprises hydrolysing the protein source to liberate at least 40% of the I-P-P- sequence into the peptide IPP and whereby a proteolytic enzyme is used which cleaves at the carboxy-terminus of proline residues present in the protein source, the enzyme is preferably a proline specific endoprotease or proline specific oligopeptidase, more preferably a proline specific endoprotease, and optionally an amino peptidase.


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